Download E-books Statistics in Clinical Vaccine Trials PDF

By Jozef Nauta

This monograph deals well-founded education and services at the statistical research of knowledge from scientific vaccine trials, i.e., immunogenicity and vaccine box efficacy reports. The book's scope is useful instead of theoretical. It opens with introductory chapters at the immunology of vaccines to supply readers with the mandatory historical past wisdom. It then maintains with an in-depth exploration of the statistical method. Many real-life examples and SAS codes are awarded, making program of the equipment common. themes mentioned comprise greatest probability estimation for censored antibody titers, ANCOVA for antibody values, research of equivalence and non-inferiority immunogenicity trial info, research of knowledge from vaccine box efficacy trials (including facts from experiences with recurrent an infection data), becoming safety curves to information of problem or box efficacy stories, and the research of vaccine security facts.

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